Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation...
Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD
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Author / Creator
Chen, Tongshuai , Liu, Junni , Li, Na , Wang, Shujian , Liu, Hui , Li, Jingyuan , Zhang, Yun and Bu, Peili
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cardiac hypertrophy is an adaptive response to pressure, volume stress, and loss of contractile mass from prior infarction. Metabolic changes in cardiac hypertrophy include suppression of fatty acid oxidation and enhancement of glucose utilization, which could result in lipid accumulation in the heart. SIRT3, a mitochondrial NAD+-dependent deacetyl...
Alternative Titles
Full title
Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1661102109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1661102109
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0118909