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Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation...

Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1661102109

Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD

About this item

Full title

Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-03, Vol.10 (3), p.e0118909-e0118909

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Cardiac hypertrophy is an adaptive response to pressure, volume stress, and loss of contractile mass from prior infarction. Metabolic changes in cardiac hypertrophy include suppression of fatty acid oxidation and enhancement of glucose utilization, which could result in lipid accumulation in the heart. SIRT3, a mitochondrial NAD+-dependent deacetyl...

Alternative Titles

Full title

Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1661102109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1661102109

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0118909

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