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A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates coll...

A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates coll...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1663912132

A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells

About this item

Full title

A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-03, Vol.10 (3), p.e0116006-e0116006

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

During tumour dissemination, invading breast carcinoma cells become confronted with a reactive stroma, a type I collagen-rich environment endowed with anti-proliferative and pro-apoptotic properties. To develop metastatic capabilities, tumour cells must acquire the capacity to cope with this novel microenvironment. How cells interact with and respo...

Alternative Titles

Full title

A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1663912132

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1663912132

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0116006

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