Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein
Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Aggregation of α-synuclein (α-syn) is associated with the development of a number of neurodegenerative diseases, including Parkinson's disease (PD). The formation of α-syn aggregates results from aberrant accumulation of misfolded α-syn and insufficient or impaired activity of the two main intracellular protein degradation systems, namely the ubiqu...
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Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein
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TN_cdi_plos_journals_1664782792
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1664782792
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0120819
