All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Invol...
All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The kinase Akt is a key downstream mediator of the phosphoinositide-3-kinase signaling pathway and participates in a variety of cellular processes. Akt comprises three isoforms each encoded by a separate gene. There is evidence to indicate that Akt is involved in the survival and protection of auditory hair cells in vitro. However, little is known...
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Full title
All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear
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TN_cdi_plos_journals_1667004673
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1667004673
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0121599
