Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel ther...
Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers
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Author / Creator
Dodbiba, Lorin , Teichman, Jennifer , Fleet, Andrew , Thai, Henry , Starmans, Maud H W , Navab, Roya , Chen, Zhuo , Girgis, Hala , Eng, Lawson , Espin-Garcia, Osvaldo , Shen, Xiaowei , Bandarchi, Bizhan , Schwock, Joerg , Tsao, Ming-Sound , El-Zimaity, Hala , Der, Sandy D , Xu, Wei , Bristow, Robert G , Darling, Gail E , Boutros, Paul C , Ailles, Laurie E and Liu, Geoffrey
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The high morbidity and mortality of patients with esophageal (E) and gastro-esophageal junction (GEJ) cancers, warrants new pre-clinical models for drug testing. The utility of primary tumor xenografts (PTXGs) as pre-clinical models was assessed. Clinicopathological, immunohistochemical markers (p53, p16, Ki-67, Her-2/neu and EGFR), and global mRNA...
Alternative Titles
Full title
Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers
Authors, Artists and Contributors
Author / Creator
Teichman, Jennifer
Fleet, Andrew
Thai, Henry
Starmans, Maud H W
Navab, Roya
Chen, Zhuo
Girgis, Hala
Eng, Lawson
Espin-Garcia, Osvaldo
Shen, Xiaowei
Bandarchi, Bizhan
Schwock, Joerg
Tsao, Ming-Sound
El-Zimaity, Hala
Der, Sandy D
Xu, Wei
Bristow, Robert G
Darling, Gail E
Boutros, Paul C
Ailles, Laurie E
Liu, Geoffrey
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1667954739
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1667954739
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0121872