Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions
Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions
About this item
Full title
Author / Creator
Wang, Yu , Li, Wei , Xia, Yingying , Wang, Chongzhi , Tang, Y Tom , Guo, Wenying , Li, Jinliang , Zhao, Xia , Sun, Yepeng , Hu, Juan , Zhen, Hefu , Zhang, Xiandong , Chen, Chao , Shi, Yujian , Li, Lin , Cao, Hongzhi , Du, Hongli and Li, Jian
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Copy-number variations (CNV), loss of heterozygosity (LOH), and uniparental disomy (UPD) are large genomic aberrations leading to many common inherited diseases, cancers, and other complex diseases. An integrated tool to identify these aberrations is essential in understanding diseases and in designing clinical interventions. Previous discovery met...
Alternative Titles
Full title
Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1676336431
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676336431
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0123081
