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Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor ne...

Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1683763161

Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice

About this item

Full title

Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-05, Vol.10 (5), p.e0128007-e0128007

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Neonatal white matter injury (nWMI) is an increasingly common cause of cerebral palsy that results predominantly from hypoxic injury to progenitor cells including those of the oligodendrocyte lineage. Existing mouse models of nWMI utilize prolonged periods of hypoxia during the neonatal period, require complex cross-fostering and exhibit poor growt...

Alternative Titles

Full title

Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1683763161

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1683763161

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0128007

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