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Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Toleran...

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Toleran...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685002513

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

About this item

Full title

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2014-08, Vol.12 (8), p.e1001928

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Phenotypic heterogeneity can confer clonal groups of organisms with new functionality. A paradigmatic example is the bistable expression of virulence genes in Salmonella typhimurium, which leads to phenotypically virulent and phenotypically avirulent subpopulations. The two subpopulations have been shown to divide labor during S. typhimurium infect...

Alternative Titles

Full title

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685002513

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685002513

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1001928

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