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ArticlesPeer ReviewedFull Text
Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut
Author / Creator:Bakkeren, Erik ; Herter, Joana Anuschka ; Huisman, Jana Sanne ; Steiger, Yves ; Gül, Ersin ; Newson, Joshua Patrick Mark ; Brachmann, Alexander Oliver ; Piel, Jörn ; Regoes, Roland ; Bonhoeffer, Sebastian ; Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-12, Vol.10
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Evolutionary causes and consequences of bacterial antibiotic persistence
Author / Creator:Bakkeren, Erik ; Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2020-09, Vol.18 (9), p.479-490
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A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants
Author / Creator:Diard, Médéric ; Bakkeren, Erik ; Lentsch, Verena ; Rocker, Andrea ; Bekele, Nahimi Amare ; Hoces, Daniel ; Aslani, Selma ; Arnoldini, Markus ; Böhi, Flurina ; Schumann-Moor, Kathrin ; Adamcik, Jozef ; Piccoli, Luca ; Lanzavecchia, Antonio ; Stadtmueller, Beth M. ; Donohue, Nicholas ; van der Woude, Marjan W. ; Hockenberry, Alyson ; Viollier, Patrick H. ; Falquet, Laurent ; Wüthrich, Daniel ; Bonfiglio, Ferdinando ; Loverdo, Claude ; Egli, Adrian ; Zandomeneghi, Giorgia ; Mezzenga, Raffaele ; Holst, Otto ; Meier, Beat H. ; Hardt, Wolf-Dietrich ; Slack, Emma
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2021-07, Vol.6 (7), p.830-841
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Evolution of bacterial virulence
Author / Creator:Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:England: Oxford University Press
Journal title:FEMS microbiology reviews, 2017-09, Vol.41 (5), p.679-697
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Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
Author / Creator:Bakkeren, Erik ; Huisman, Jana S. ; Fattinger, Stefan A. ; Hausmann, Annika ; Furter, Markus ; Egli, Adrian ; Slack, Emma ; Sellin, Mikael E. ; Bonhoeffer, Sebastian ; Regoes, Roland R. ; Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-09, Vol.573 (7773), p.276-280
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Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution
Author / Creator:Slack, Emma ; Diard, Médéric
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2022-06, Vol.15 (6), p.1188-1198
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Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis
Author / Creator:Maier, Lisa ; Diard, Médéric ; Sellin, Mikael E. ; Chouffane, Elsa-Sarah ; Trautwein-Weidner, Kerstin ; Periaswamy, Balamurugan ; Slack, Emma ; Dolowschiak, Tamas ; Stecher, Bärbel ; Loverdo, Claude ; Regoes, Roland R. ; Hardt, Wolf-Dietrich
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2015-07, Vol.11 (7), p.e1005047-e1005047
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ArticlesPeer ReviewedFull Text
High-avidity IgA protects the intestine by enchaining growing bacteria
Author / Creator:Moor, Kathrin ; Diard, Médéric ; Sellin, Mikael E. ; Felmy, Boas ; Wotzka, Sandra Y. ; Toska, Albulena ; Bakkeren, Erik ; Arnoldini, Markus ; Bansept, Florence ; Co, Alma Dal ; Völler, Tom ; Minola, Andrea ; Fernandez-Rodriguez, Blanca ; Agatic, Gloria ; Barbieri, Sonia ; Piccoli, Luca ; Casiraghi, Costanza ; Corti, Davide ; Lanzavecchia, Antonio ; Regoes, Roland R. ; Loverdo, Claude ; Stocker, Roman ; Brumley, Douglas R. ; Hardt, Wolf-Dietrich ; Slack, Emma
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-04, Vol.544 (7651), p.498-502
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Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice
Author / Creator:Wotzka, Sandra Y. ; Kreuzer, Markus ; Maier, Lisa ; Arnoldini, Markus ; Nguyen, Bidong D. ; Brachmann, Alexander O. ; Berthold, Dorothée L. ; Zünd, Mirjam ; Hausmann, Annika ; Bakkeren, Erik ; Hoces, Daniel ; Gül, Ersin ; Beutler, Markus ; Dolowschiak, Tamas ; Zimmermann, Michael ; Fuhrer, Tobias ; Moor, Kathrin ; Sauer, Uwe ; Typas, Athanasios ; Piel, Jörn ; Diard, Médéric ; Macpherson, Andrew J. ; Stecher, Bärbel ; Sunagawa, Shinichi ; Slack, Emma ; Hardt, Wolf-Dietrich
Journal title:Nature microbiology, 2019-12, Vol.4 (12), p.2164-2174
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Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium
Author / Creator:Bakkeren, Erik ; Gül, Ersin ; Huisman, Jana S. ; Steiger, Yves ; Rocker, Andrea ; Hardt, Wolf-Dietrich ; Diard, Médéric
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.1939-1939, Article 1939
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Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo
Author / Creator:Benz, Fabienne ; Huisman, Jana S. ; Bakkeren, Erik ; Herter, Joana A. ; Stadler, Tanja ; Ackermann, Martin ; Diard, Médéric ; Egli, Adrian ; Hall, Alex R. ; Hardt, Wolf-Dietrich ; Bonhoeffer, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:The ISME Journal, 2021-03, Vol.15 (3), p.862-878
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Stabilization of cooperative virulence by the expression of an avirulent phenotype
Author / Creator:Diard, Médéric ; Garcia, Victor ; Maier, Lisa ; Remus-Emsermann, Mitja N. P. ; Regoes, Roland R. ; Ackermann, Martin ; Hardt, Wolf-Dietrich
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-02, Vol.494 (7437), p.353-356
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Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation
Author / Creator:Arnoldini, Markus ; Vizcarra, Ima Avalos ; Peña-Miller, Rafael ; Stocker, Nicolas ; Diard, Médéric ; Vogel, Viola ; Beardmore, Robert E. ; Hardt, Wolf-Dietrich ; Ackermann, Martin
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2014-08, Vol.12 (8), p.e1001928
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Diagnosing and engineering gut microbiomes
Author / Creator:Cappio Barazzone, Elisa ; Diard, Médéric ; Hug, Isabelle ; Larsson, Louise ; Slack, Emma
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2024-11, Vol.16 (11), p.2660-2677
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The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium
Author / Creator:Sobota, Malgorzata ; Rodilla Ramirez, Pilar Natalia ; Cambré, Alexander ; Rocker, Andrea ; Mortier, Julien ; Gervais, Théo ; Haas, Tiphaine ; Cornillet, Delphine ; Chauvin, Dany ; Hug, Isabelle ; Julou, Thomas ; Aertsen, Abram ; Diard, Médéric
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2022-04, Vol.20 (4), p.e3001608
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Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
Author / Creator:Hausmann, Annika ; Böck, Desirée ; Geiser, Petra ; Berthold, Dorothée L. ; Fattinger, Stefan A. ; Furter, Markus ; Bouman, Judith A. ; Barthel-Scherrer, Manja ; Lang, Crispin M. ; Bakkeren, Erik ; Kolinko, Isabel ; Diard, Médéric ; Bumann, Dirk ; Slack, Emma ; Regoes, Roland R. ; Pilhofer, Martin ; Sellin, Mikael E. ; Hardt, Wolf-Dietrich
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2020-05, Vol.13 (3), p.530-544
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The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium
Author / Creator:Colgan, Aoife M. ; Kröger, Carsten ; Diard, Médéric ; Hardt, Wolf-Dietrich ; Puente, José L. ; Sivasankaran, Sathesh K. ; Hokamp, Karsten ; Hinton, Jay C. D.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2016-08, Vol.12 (8), p.e1006258-e1006258
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Evolution bakterieller Virulenz
Author / Creator:Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Biospektrum, 2018-05, Vol.24 (3), p.338-338
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Inflammation boosts bacteriophage transfer between Salmonella spp
Author / Creator:Diard, Médéric ; Bakkeren, Erik ; Cornuault, Jeffrey K. ; Moor, Kathrin ; Hausmann, Annika ; Sellin, Mikael E. ; Loverdo, Claude ; Aertsen, Abram ; Ackermann, Martin ; De Paepe, Marianne ; Slack, Emma ; Hardt, Wolf-Dietrich
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6330), p.1211-1215
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The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence
Author / Creator:Gül, Ersin ; Bakkeren, Erik ; Salazar, Guillem ; Steiger, Yves ; Abi Younes, Andrew ; Clerc, Melanie ; Christen, Philipp ; Fattinger, Stefan A. ; Nguyen, Bidong D. ; Kiefer, Patrick ; Slack, Emma ; Ackermann, Martin ; Vorholt, Julia A. ; Sunagawa, Shinichi ; Diard, Médéric ; Hardt, Wolf-Dietrich
Publisher:San Francisco: Public Library of Science
Journal title:PLoS biology, 2023-08, Vol.21 (8), p.e3002253
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Showing 1 to 20 of 35 results

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Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut

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Evolutionary causes and consequences of bacterial antibiotic persistence

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A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

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Evolution of bacterial virulence

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Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut

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Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution

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Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis

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High-avidity IgA protects the intestine by enchaining growing bacteria

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Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

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Impact of horizontal gene transfer on emergence and stability of cooperative virulence in Salmonella Typhimurium

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Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo

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Stabilization of cooperative virulence by the expression of an avirulent phenotype

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Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

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Diagnosing and engineering gut microbiomes

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The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium

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Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression

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The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium

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Evolution bakterieller Virulenz

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Inflammation boosts bacteriophage transfer between Salmonella spp

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The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence

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