Modulation of the maladaptive stress response to manage diseases of protein folding
Modulation of the maladaptive stress response to manage diseases of protein folding
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Diseases of protein folding arise because of the inability of an altered peptide sequence to properly engage protein homeostasis components that direct protein folding and function. To identify global principles of misfolding disease pathology we examined the impact of the local folding environment in alpha-1-antitrypsin deficiency (AATD), Niemann-...
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Full title
Modulation of the maladaptive stress response to manage diseases of protein folding
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TN_cdi_plos_journals_1685008980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685008980
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001998
