Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription
Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Protein quality control is essential for clearing misfolded and aggregated proteins from the cell, and its failure is associated with many neurodegenerative disorders. Here, we identify two genes, ufd-2 and spr-5, that when inactivated, synergistically and robustly suppress neurotoxicity associated with misfolded proteins in Caenorhabditis elegans....
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Full title
Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription
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TN_cdi_plos_journals_1685024690
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685024690
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1002114
