Structure-Based Druggability Assessment of the Mammalian Structural Proteome with Inclusion of Light...
Structure-Based Druggability Assessment of the Mammalian Structural Proteome with Inclusion of Light Protein Flexibility
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Advances reported over the last few years and the increasing availability of protein crystal structure data have greatly improved structure-based druggability approaches. However, in practice, nearly all druggability estimation methods are applied to protein crystal structures as rigid proteins, with protein flexibility often not directly addressed...
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Full title
Structure-Based Druggability Assessment of the Mammalian Structural Proteome with Inclusion of Light Protein Flexibility
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TN_cdi_plos_journals_1685028854
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685028854
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1003741
