Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significan...
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation
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Author / Creator
Alzheimer's Disease Neuroimaging Initiative , the Alzheimer's Disease Neuroimaging Initiative , Kauwe, John S K , Bailey, Matthew H , Ridge, Perry G , Perry, Rachel , Wadsworth, Mark E , Hoyt, Kaitlyn L , Staley, Lyndsay A , Karch, Celeste M , Harari, Oscar , Cruchaga, Carlos , Ainscough, Benjamin J , Bales, Kelly , Pickering, Eve H , Bertelsen, Sarah , Fagan, Anne M , Holtzman, David M , Morris, John C and Goate, Alison M
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cerebrospinal fluid (CSF) 42 amino acid species of amyloid beta (Aβ42) and tau levels are strongly correlated with the presence of Alzheimer's disease (AD) neuropathology including amyloid plaques and neurodegeneration and have been successfully used as endophenotypes for genetic studies of AD. Additional CSF analytes may also serve as useful endop...
Alternative Titles
Full title
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation
Authors, Artists and Contributors
Author / Creator
the Alzheimer's Disease Neuroimaging Initiative
Kauwe, John S K
Bailey, Matthew H
Ridge, Perry G
Perry, Rachel
Wadsworth, Mark E
Hoyt, Kaitlyn L
Staley, Lyndsay A
Karch, Celeste M
Harari, Oscar
Cruchaga, Carlos
Ainscough, Benjamin J
Bales, Kelly
Pickering, Eve H
Bertelsen, Sarah
Fagan, Anne M
Holtzman, David M
Morris, John C
Goate, Alison M
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685129949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685129949
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004758