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Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685136194

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

About this item

Full title

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2014-12, Vol.10 (12), p.e1004824-e1004824

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used an experimental microevolution approach to show th...

Alternative Titles

Full title

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685136194

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685136194

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004824

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