The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocer...
The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
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Author / Creator
Chatterjee, Arpita , Saha, Saikat , Chakraborty, Anirban , Silva-Fernandes, Anabela , Mandal, Santi M. , Neves-Carvalho, Andreia , Liu, Yongping , Pandita, Raj K. , Hegde, Muralidhar L. , Hegde, Pavana M. , Boldogh, Istvan , Ashizawa, Tetsuo , Koeppen, Arnulf H. , Pandita, Tej K. , Maciel, Patricia , Sarkar, Partha S. and Hazra, Tapas K.
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
DNA strand-breaks (SBs) with non-ligatable ends are generated by ionizing radiation, oxidative stress, various chemotherapeutic agents, and also as base excision repair (BER) intermediates. Several neurological diseases have already been identified as being due to a deficiency in DNA end-processing activities. Two common dirty ends, 3'-P and 5'-OH,...
Alternative Titles
Full title
The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
Authors, Artists and Contributors
Author / Creator
Saha, Saikat
Chakraborty, Anirban
Silva-Fernandes, Anabela
Mandal, Santi M.
Neves-Carvalho, Andreia
Liu, Yongping
Pandita, Raj K.
Hegde, Muralidhar L.
Hegde, Pavana M.
Boldogh, Istvan
Ashizawa, Tetsuo
Koeppen, Arnulf H.
Pandita, Tej K.
Maciel, Patricia
Sarkar, Partha S.
Hazra, Tapas K.
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685137278
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685137278
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004749
