Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant i...
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes
About this item
Full title
Author / Creator
Prescott, Natalie J , Lehne, Benjamin , Stone, Kristina , Lee, James C , Taylor, Kirstin , Knight, Jo , Papouli, Efterpi , Mirza, Muddassar M , Simpson, Michael A , Spain, Sarah L , Lu, Grace , Fraternali, Franca , Bumpstead, Suzannah J , Gray, Emma , Amar, Ariella , Bye, Hannah , Green, Peter , Chung-Faye, Guy , Hayee, Bu'Hussain , Pollok, Richard , Satsangi, Jack , Parkes, Miles , Barrett, Jeffrey C , Mansfield, John C , Sanderson, Jeremy , Lewis, Cathryn M , Weale, Michael E , Schlitt, Thomas , Mathew, Christopher G and UK IBD Genetics Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The contribution of rare coding sequence variants to genetic susceptibility in complex disorders is an important but unresolved question. Most studies thus far have investigated a limited number of genes from regions which contain common disease associated variants. Here we investigate this in inflammatory bowel disease by sequencing the exons and...
Alternative Titles
Full title
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes
Authors, Artists and Contributors
Author / Creator
Lehne, Benjamin
Stone, Kristina
Lee, James C
Taylor, Kirstin
Knight, Jo
Papouli, Efterpi
Mirza, Muddassar M
Simpson, Michael A
Spain, Sarah L
Lu, Grace
Fraternali, Franca
Bumpstead, Suzannah J
Gray, Emma
Amar, Ariella
Bye, Hannah
Green, Peter
Chung-Faye, Guy
Hayee, Bu'Hussain
Pollok, Richard
Satsangi, Jack
Parkes, Miles
Barrett, Jeffrey C
Mansfield, John C
Sanderson, Jeremy
Lewis, Cathryn M
Weale, Michael E
Schlitt, Thomas
Mathew, Christopher G
UK IBD Genetics Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685138768
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685138768
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004955
