Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive...
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy
About this item
Full title
Author / Creator
Elliott, Julian H , Wightman, Fiona , Solomon, Ajantha , Ghneim, Khader , Ahlers, Jeffrey , Cameron, Mark J , Smith, Miranda Z , Spelman, Tim , McMahon, James , Velayudham, Pushparaj , Brown, Gregor , Roney, Janine , Watson, Jo , Prince, Miles H , Hoy, Jennifer F , Chomont, Nicolas , Fromentin, Rémi , Procopio, Francesco A , Zeidan, Joumana , Palmer, Sarah , Odevall, Lina , Johnstone, Ricky W , Martin, Ben P , Sinclair, Elizabeth , Deeks, Steven G , Hazuda, Daria J , Cameron, Paul U , Sékaly, Rafick-Pierre and Lewin, Sharon R
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Human immunodeficiency virus (HIV) persistence in latently infected resting memory CD4+ T-cells is the major barrier to HIV cure. Cellular histone deacetylases (HDACs) are important in maintaining HIV latency and histone deacetylase inhibitors (HDACi) may reverse latency by activating HIV transcription from latently infected CD4+ T-cells. We perfor...
Alternative Titles
Full title
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy
Authors, Artists and Contributors
Author / Creator
Wightman, Fiona
Solomon, Ajantha
Ghneim, Khader
Ahlers, Jeffrey
Cameron, Mark J
Smith, Miranda Z
Spelman, Tim
McMahon, James
Velayudham, Pushparaj
Brown, Gregor
Roney, Janine
Watson, Jo
Prince, Miles H
Hoy, Jennifer F
Chomont, Nicolas
Fromentin, Rémi
Procopio, Francesco A
Zeidan, Joumana
Palmer, Sarah
Odevall, Lina
Johnstone, Ricky W
Martin, Ben P
Sinclair, Elizabeth
Deeks, Steven G
Hazuda, Daria J
Cameron, Paul U
Sékaly, Rafick-Pierre
Lewin, Sharon R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685289704
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685289704
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004473
