The role of the NADPH oxidase NOX2 in prion pathogenesis
The role of the NADPH oxidase NOX2 in prion pathogenesis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Prion infections cause neurodegeneration, which often goes along with oxidative stress. However, the cellular source of reactive oxygen species (ROS) and their pathogenetic significance are unclear. Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion diseases. We found that NOX2 is markedly upregulated in microglia within...
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Full title
The role of the NADPH oxidase NOX2 in prion pathogenesis
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TN_cdi_plos_journals_1685292564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685292564
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004531
