Structural determinants of phenotypic diversity and replication rate of human prions
Structural determinants of phenotypic diversity and replication rate of human prions
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The infectious pathogen responsible for prion diseases is the misfolded, aggregated form of the prion protein, PrPSc. In contrast to recent progress in studies of laboratory rodent-adapted prions, current understanding of the molecular basis of human prion diseases and, especially, their vast phenotypic diversity is very limited. Here, we have puri...
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Full title
Structural determinants of phenotypic diversity and replication rate of human prions
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TN_cdi_plos_journals_1685369270
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685369270
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004832
