Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of w...
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change
About this item
Full title
Author / Creator
Würtz, Peter , Wang, Qin , Kangas, Antti J , Richmond, Rebecca C , Skarp, Joni , Tiainen, Mika , Tynkkynen, Tuulia , Soininen, Pasi , Havulinna, Aki S , Kaakinen, Marika , Viikari, Jorma S , Savolainen, Markku J , Kähönen, Mika , Lehtimäki, Terho , Männistö, Satu , Blankenberg, Stefan , Zeller, Tanja , Laitinen, Jaana , Pouta, Anneli , Mäntyselkä, Pekka , Vanhala, Mauno , Elliott, Paul , Pietiläinen, Kirsi H , Ripatti, Samuli , Salomaa, Veikko , Raitakari, Olli T , Järvelin, Marjo-Riitta , Smith, George Davey and Ala-Korpela, Mika
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Increased adiposity is linked with higher risk for cardiometabolic diseases. We aimed to determine to what extent elevated body mass index (BMI) within the normal weight range has causal effects on the detailed systemic metabolite profile in early adulthood.
We used Mendelian randomization to estimate causal effects of BMI on 82 metabolic measur...
Alternative Titles
Full title
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change
Authors, Artists and Contributors
Author / Creator
Wang, Qin
Kangas, Antti J
Richmond, Rebecca C
Skarp, Joni
Tiainen, Mika
Tynkkynen, Tuulia
Soininen, Pasi
Havulinna, Aki S
Kaakinen, Marika
Viikari, Jorma S
Savolainen, Markku J
Kähönen, Mika
Lehtimäki, Terho
Männistö, Satu
Blankenberg, Stefan
Zeller, Tanja
Laitinen, Jaana
Pouta, Anneli
Mäntyselkä, Pekka
Vanhala, Mauno
Elliott, Paul
Pietiläinen, Kirsi H
Ripatti, Samuli
Salomaa, Veikko
Raitakari, Olli T
Järvelin, Marjo-Riitta
Smith, George Davey
Ala-Korpela, Mika
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685420632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685420632
Other Identifiers
ISSN
1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.1001765
