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Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocyst...

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocyst...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686065103

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)

About this item

Full title

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0127349-e0127349

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Selenocysteine tRNA 1 associated protein (Trnau1ap) has been characterized as a tRNA[Ser]Sec-binding protein of 43 kDa, hence initially named SECp43. Previous studies reported its presence in complexes containing tRNA[Ser]Sec implying a role of SECp43 as a co-factor in selenoprotein expression. We generated two conditionally mutant mouse models tar...

Alternative Titles

Full title

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1686065103

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686065103

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0127349

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