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Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MS...

Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MS...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686781442

Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome

About this item

Full title

Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0130018-e0130018

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lynch syndrome, caused by germline mutations in mismatch repair genes, is a predisposing factor for colorectal cancer (CRC). This retrospective cohort study investigated the risk factors associated with the development of CRC in patients with MLH1 and MSH2 germline mutations.
In total, 301 MLH1 and MSH2 germline mutation carriers were identified...

Alternative Titles

Full title

Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in MLH1 and MSH2 in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1686781442

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686781442

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0130018

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