The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Pres...
The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Human genetic and animal studies have implicated the costimulatory molecule CD40 in the development of multiple sclerosis (MS). We investigated the cell specific gene and protein expression variation controlled by the CD40 genetic variant(s) associated with MS, i.e. the T-allele at rs1883832. Previously we had shown that the risk allele is expresse...
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The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function
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TN_cdi_plos_journals_1687640347
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1687640347
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0127080
