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Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of...

Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1689845787

Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers

About this item

Full title

Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0130142-e0130142

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The potential predictive role of programmed death-ligand-1 (PD-L1) expression on tumor cells in the context of solid tumor treated with checkpoint inhibitors targeting the PD-1 pathway represents an issue for clinical research.
Overall response rate (ORR) was extracted from phase I-III trials investigating nivolumab, pembrolizumab and MPDL3280A...

Alternative Titles

Full title

Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1689845787

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1689845787

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0130142

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