Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Functio...
Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Elongation factor 1A-1 (eEF1A-1) has non-canonical functions in regulation of the actin cytoskeleton and apoptosis. It was previously identified through a promoter-trap screen as a mediator of fatty acid-induced cell death (lipotoxicity), and was found to participate in this process downstream of ER stress. Since ER stress is implicated in the path...
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Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis
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TN_cdi_plos_journals_1690656121
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1690656121
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0131269
