Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity i...
Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Tamoxifen resistance is often observed in the majority of estrogen receptor-positive breast cancers and it remains as a serious clinical problem in breast cancer management. Increased aerobic glycolysis has been proposed as one of the mechanisms for acquired resistance to chemotherapeutic agents in breast cancer cells such as adriamycin. Herein, we...
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Full title
Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells
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TN_cdi_plos_journals_1695157121
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1695157121
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0132285
