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Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain E...

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain E...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1696855946

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

About this item

Full title

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2015-06, Vol.11 (6), p.e1004965

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The opportunistic intracellular pathogen Legionella pneumophila is the causative agent of Legionnaires' disease. L. pneumophila delivers nearly 300 effector proteins into host cells for the establishment of a replication-permissive compartment known as the Legionella-containing vacuole (LCV). SidC and its paralog SdcA are two effectors that have be...

Alternative Titles

Full title

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1696855946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1696855946

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1004965

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