Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
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Full title
Author / Creator
Lei, Wenjing , Long, Yanjun , Li, Shuang , Liu, Ze , Zhu, Fengxin , Hou, Fan Fan and Nie, Jing
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Hyperhomocysteinemia (HHcy) leads to several clinical manifestations including hepatic fibrosis. Excess deposition of extracellular matrix (ECM) components including collagen is the eponymous lesion of liver fibrosis. In this study, we demonstrated that elevated concentration of Hcy induced the expression of collagen type I in cultured human liver...
Alternative Titles
Full title
Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1697422623
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1697422623
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0130421
