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Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Huma...

Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1697759049

Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells

About this item

Full title

Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-07, Vol.10 (7), p.e0133743

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The alkylating agent bendamustine is approved for the treatment of hematopoietic malignancies such as non-Hodgkin lymphoma, chronic lymphocytic leukemia and multiple myeloma. As preliminary data on recently disclosed bendamustine esters suggested increased cytotoxicity, we investigated representative derivatives in more detail. Especially basic est...

Alternative Titles

Full title

Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1697759049

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1697759049

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0133743

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