Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity
Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Skeletal muscle aging is associated with a decreased regenerative potential due to the loss of function of endogenous stem cells or myogenic progenitor cells (MPCs). Aged skeletal muscle is characterized by the deposition of extracellular matrix (ECM), which in turn influences the biomechanical properties of myofibers by increasing their stiffness....
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Full title
Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity
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TN_cdi_plos_journals_1708482363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482363
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136217
