Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulatio...
Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Scope and Contents
Contents
Small molecule inhibitors against protein geranylgeranyltransferase-I such as P61A6 have been shown to inhibit proliferation of a variety of human cancer cells and exhibit antitumor activity in mouse models. Development of these inhibitors could be dramatically accelerated by conferring tumor targeting and controlled release capability. As a first...
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Full title
Nanoformulation of Geranylgeranyltransferase-I Inhibitors for Cancer Therapy: Liposomal Encapsulation and pH-Dependent Delivery to Cancer Cells
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TN_cdi_plos_journals_1715677917
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1715677917
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0137595
