Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Pola...
Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Estrogen receptor α (ERα), as a ligand-dependent transcription factor, mediates 17β-estradiol (E2) effects. ERα is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino- and carboxyl-termini. The interaction of the E2-activated ERα dimer with estrogen response elements (EREs) of genes...
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Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators
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TN_cdi_plos_journals_1719000129
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719000129
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136423
