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Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Pola...

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Pola...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719000129

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

About this item

Full title

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-08, Vol.10 (8), p.e0136423-e0136423

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Estrogen receptor α (ERα), as a ligand-dependent transcription factor, mediates 17β-estradiol (E2) effects. ERα is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino- and carboxyl-termini. The interaction of the E2-activated ERα dimer with estrogen response elements (EREs) of genes...

Alternative Titles

Full title

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1719000129

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719000129

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0136423

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