Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected...
Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Prion diseases are neurodegenerative disorders caused by the accumulation of abnormal prion protein (PrPSc) in the central nervous system. With the aim of elucidating the mechanism underlying the accumulation and degradation of PrPSc, we investigated the role of autophagy in its degradation, using cultured cells stably infected with distinct prion...
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Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells
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TN_cdi_plos_journals_1719284564
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719284564
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0137958
