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Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer'...

Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer'...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719292390

Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up

About this item

Full title

Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-09, Vol.10 (9), p.e0138326-e0138326

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recent findings indicate that microglia in Alzheimer's disease (AD) is senescent whereas peripheral blood mononuclear cells (PBMCs) could infiltrate the brain to phagocyte amyloid deposits. However, the molecular mechanisms involved in the amyloid peptide clearance remain unknown. Autophagy is a physiological degradation of proteins and organelles...

Alternative Titles

Full title

Inflammatory Stress on Autophagy in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease during 24 Months of Follow-Up

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1719292390

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719292390

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0138326

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