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Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Tr...

Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Tr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1722473230

Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle

About this item

Full title

Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-10, Vol.10 (10), p.e0140471-e0140471

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

30 years ago, the potential of bispecific antibodies to engage cytotoxic T cells for the lysis of cancer cells was discovered. Today a variety of bispecific antibodies against diverse cell surface structures have been developed, the majority of them produced in mammalian cell culture systems. Beside the r28M, described here, no such bispecific anti...

Alternative Titles

Full title

Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1722473230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1722473230

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0140471

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