Prolonged Subdural Infusion of Kynurenic Acid Is Associated with Dose-Dependent Myelin Damage in the...
Prolonged Subdural Infusion of Kynurenic Acid Is Associated with Dose-Dependent Myelin Damage in the Rat Spinal Cord
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Kynurenic acid (KYNA) is the end stage metabolite of tryptophan produced mainly by astrocytes in the central nervous system (CNS). It has neuroprotective activities but can be elevated in the neuropsychiatric disorders. Toxic effects of KYNA in the CNS are unknown. The aim of this study was to assess the effect of the subdural KYNA infusion on the...
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Prolonged Subdural Infusion of Kynurenic Acid Is Associated with Dose-Dependent Myelin Damage in the Rat Spinal Cord
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TN_cdi_plos_journals_1733201358
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1733201358
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0142598