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BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transge...

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transge...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1738477730

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

About this item

Full title

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-12, Vol.10 (12), p.e0143688

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The molecular mechanisms driving the papillary thyroid carcinoma (PTC) are still poorly understood. The most frequent genetic alteration in PTC is the BRAFV600E mutation--its impact may extend even beyond PTC genomic profile and influence the tumor characteristics and even clinical behavior.
In order to identify BRAF-dependent signature of early...

Alternative Titles

Full title

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1738477730

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1738477730

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0143688

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