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The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memo...

The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1749631442

The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

About this item

Full title

The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2015-11, Vol.13 (11), p.e1002290-e1002290

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

IgE-mediated activation of mast cells and basophils contributes to protective immunity against helminths but also causes allergic responses. The development and persistence of IgE responses are poorly understood, which is in part due to the low number of IgE-producing cells. Here, we used next generation sequencing to uncover a striking overlap bet...

Alternative Titles

Full title

The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1749631442

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1749631442

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1002290

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