Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Integrating single nucleotide polymorphism (SNP) p-values from genome-wide association studies (GWAS) across genes and pathways is a strategy to improve statistical power and gain biological insight. Here, we present Pascal (Pathway scoring algorithm), a powerful tool for computing gene and pathway scores from SNP-phenotype association summary stat...
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Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
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TN_cdi_plos_journals_1764351819
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1764351819
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1004714
