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DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nu...

DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771736717

DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis

About this item

Full title

DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-03, Vol.11 (3), p.e0150189-e0150189

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA backbone contacts and selects target sites by reading conformational properties of DNA sequences, most prominently intrinsic minor groove widths. High-affinity binding requires...

Alternative Titles

Full title

DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1771736717

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1771736717

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0150189

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