Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tu...
Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Tubular injury is one of the important determinants of progressive renal failure in diabetic nephropathy (DN), and TGF-β1 has been implicated in the pathogenesis of tubulointerstitial disease that characterizes proteinuric renal disease. The aim of this study was to identify novel therapeutic target molecules that play a role in the tubule damage o...
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Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells
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TN_cdi_plos_journals_1773263104
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1773263104
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0150897