Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Eme...
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Pharmacologic stimulation of innate immune processes represents an attractive strategy to achieve multiple therapeutic outcomes including inhibition of virus replication, boosting antitumor immunity, and enhancing vaccine immunogenicity. In light of this we sought to identify small molecules capable of activating the type I interferon (IFN) respons...
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Full title
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses
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TN_cdi_plos_journals_1773863167
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1773863167
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005324
