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Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immuni...

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immuni...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1773863248

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection

About this item

Full title

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2015-12, Vol.11 (12), p.e1005338-e1005338

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Influenza A virus (IAV) is an airborne pathogen that causes significant morbidity and mortality each year. Macrophages (Mϕ) are the first immune population to encounter IAV virions in the lungs and are required to control infection. In the present study, we explored the mechanism by which cytokine signaling regulates the phenotype and function of M...

Alternative Titles

Full title

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1773863248

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1773863248

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1005338

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