A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania a...
A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Iron, an essential co-factor of respiratory chain proteins, is critical for mitochondrial function and maintenance of its redox balance. We previously reported a role for iron uptake in differentiation of Leishmania amazonensis into virulent amastigotes, by a mechanism that involves reactive oxygen species (ROS) production and is independent of the...
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Full title
A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence
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TN_cdi_plos_journals_1777266728
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1777266728
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1005340
