Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling
Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms α and β) have impaired expansive arterial remodeling due to diminished expression of matrix-degrading enzymes, especially MMP-3. Emergence of IL-1 as a target in cardiovascular disease prompted the investigation of the redundancy of IL-1α and IL-1β in the induction of MMP-3...
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Full title
Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling
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TN_cdi_plos_journals_1777533709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1777533709
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0152474
