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An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1778407821

An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

About this item

Full title

An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-04, Vol.11 (4), p.e0152679-e0152679

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A common way to study protein function is to deplete the protein of interest from cells and observe the response. Traditional methods involve disrupting gene expression but these techniques are only effective against newly synthesized proteins and leave previously existing and stable proteins untouched. Here, we introduce a technique that induces t...

Alternative Titles

Full title

An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1778407821

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1778407821

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0152679

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