ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production
ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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ATP-binding cassette G1 (ABCG1) and ABCG4, expressed in neurons and glia in the central nervous system, mediate cholesterol efflux to lipid acceptors. The relationship between cholesterol level in the central nervous system and Alzheimer's disease has been reported. In this study, we examined the effects of ABCG1 and ABCG4 on amyloid precursor prot...
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ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production
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TN_cdi_plos_journals_1790062897
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1790062897
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0155400
