Functional and Structural Analyses of CYP1B1 Variants Linked to Congenital and Adult-Onset Glaucoma...
Functional and Structural Analyses of CYP1B1 Variants Linked to Congenital and Adult-Onset Glaucoma to Investigate the Molecular Basis of These Diseases
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Glaucoma, the leading cause of irreversible blindness, appears in various forms. Mutations in CYP1B1 result in primary congenital glaucoma (PCG) by an autosomal recessive mode of inheritance while it acts as a modifier locus for primary open angle glaucoma (POAG). We investigated the molecular basis of the variable phenotypes resulting from the def...
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Functional and Structural Analyses of CYP1B1 Variants Linked to Congenital and Adult-Onset Glaucoma to Investigate the Molecular Basis of These Diseases
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TN_cdi_plos_journals_1792773206
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1792773206
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0156252
