Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensiti...
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
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Penterling, Corina , Drexler, Guido A , Böhland, Claudia , Stamp, Ramona , Wilke, Christina , Braselmann, Herbert , Caldwell, Randolph B , Reindl, Judith , Girst, Stefanie , Greubel, Christoph , Siebenwirth, Christian , Mansour, Wael Y , Borgmann, Kerstin , Dollinger, Günther , Unger, Kristian and Friedl, Anna A
Publisher
United States: Public Library of Science
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English
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Publisher
United States: Public Library of Science
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Contents
Histone demethylases have recently gained interest as potential targets in cancer treatment and several histone demethylases have been implicated in the DNA damage response. We investigated the effects of siRNA-mediated depletion of histone demethylase Jarid1A (KDM5A, RBP2), which demethylates transcription activating tri- and dimethylated lysine 4...
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Full title
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
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TN_cdi_plos_journals_1793571494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1793571494
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0156599
