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Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1797504427

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

About this item

Full title

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2016-05, Vol.12 (5), p.e1005656-e1005656

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lassa fever (LASF) is a highly severe viral syndrome endemic to West African countries. Despite the annual high morbidity and mortality caused by LASF, very little is known about the pathophysiology of the disease. Basic research on LASF has been precluded due to the lack of relevant small animal models that reproduce the human disease. Immunocompe...

Alternative Titles

Full title

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1797504427

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1797504427

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1005656

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